منابع مشابه
Influence of Doxapram Hydrochloride on Recovery from Thiopental Anaesthesia.
MAN~ DaWS known as respiratory stimulants have been covely from pmsonmg by barbiturates and other sedat:ve have also been used to inmate and sustain breathing accelerate the rate of recovery from general anaesthes:a mon practice m years past has been to add carbon dmnl, of an anaesthetac to accomphsh this goal Even thoug prachces may be inherently dangerous, they are still used Recently, severa...
متن کاملThe Analeptic Effects of Doxapram Hydrochloride on Thiopentone Induced Depression.
A study of the analeptic properties of doxapram hydrochloride, as judged by its effects on the depression induced by moderate doses of thiopentone, was carried out in sixty patients. Three dose levels of the drug were employed, all of which produced marked increases in alveolar ventilation. These increases were due almost entirely to effects on tidal volume. Although the initial peak of stimula...
متن کاملDoxapram Hydrochloride Aggravates Adrenaline-Induced Arrhythmias Accompanied by Bidirectional Ventricular Tachycardia
Objectives. Doxapram hydrochloride is a respiratory stimulant that has an inhibitory effect on myocardial IK1 potassium channels and is thought to increase membrane instability and excitability in myocardial cells. We examined the arrhythmogenic effects of doxapram hydrochloride in a rat model of halothane adrenaline-induced arrhythmia. Methods. Thirteen female Wistar rats (12-14 weeks old) wer...
متن کاملPanic attacks induced by doxapram.
Doxapram is a respiratory stimulant thought to act by stimulating medullary neurones and carotid oxygen receptors (Kato and Buckley 1964). It changes neither oxygen uptake nor CO2 production, but produces substantial hyperventilation (Calvedey et al 1983). Hyperventilation occurs during naturally occurring or pharmacologically induced panic attacks, and perhaps also in panic patients between at...
متن کاملEffects of doxapram on postoperative pulmonary complications following thoracotomy.
An i.v. solution of 5% dextrose with doxapram 2 mg ml-1 or 5% dextrose alone was administered to 53 patients following lateral thoracotomy. Estimations of arterial PO2, PCO2 and pH were made before operation, during infusion and 7 days after after operation. Respiratory function tests were carried out before and 7 days after operation. There were no significant differences in arterial PO2, PCO2...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1974
ISSN: 0007-0912
DOI: 10.1093/bja/46.2.169